Catalog No: OATA00211
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OATA00211
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Datasheets/ManualsPrintable datasheet for OATA00211
Product Info
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityBaboon, Canine, Chimpanzee, Cynomolgus, Equine, Feline, Rhesus, Swine
Product FormatLiquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2
ClonalityMonoclonal
CloneIM7
IsotypeRat IgG2b, kappa
HostRat
ConjugationFITC: Fluorescein Isothiocyanate
ApplicationFC
::Excitation Laser: Blue (488 nm)
::Emmision: 520 nm
Reconstitution and Storage2-8C protected from light
SpecificityCD44
Application InfoThis antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.
Reference

Chandler HL, Haeussler DJ, Gemensky-Metzler AJ, Wilkie DA, and Lutz EA. 2012. Invest. Ophthalmol. Vis. Sci. 53:1835-1845. (in vitro blocking, canine)

Lee L-F, Logronio K, Tu GH, Zhai W, Ni I, Mei L, Dilley J, Yu J, et al. 2012. Proc. Natl. Acad. Sci. 10.1073. (Flow cytometry).

Ruffell B, Poon GFT, Lee SSM, Brown KL, Tjew S-L, Cooper J, and Johnson P. 2011. J. Biol. Chem. 286:19179-19190. (Immunoprecipitation)

Miyake Y, Matsumoto H, Yokoo M, Miyazawa K et al. 2006. Biol. Reprod. 74: 501-510. (Immunohistochemistry - frozen tissue, swine)

Veir JK, Lappin MR, and Dow SW. 2006. Journal of Feline Medicine and Surgery. 8:400-411. (Flow cytometry - feline)

Frank NY, Margaryan A, Huang Y, Schatton T, Waaga-Gasser AM, Gasser M, Sayegh MH, Sadee W, and Frank MH. 2005. Cancer Res. 65:4320-4333. (Immunohistochemistry - frozen tissue)

Fischer A, Schumacher N, Maier M, Sendtner M, and Gessler M. 2004. Genes & Dev. 18:901-911. (Immunohistochemistry - paraffin embedded tissue)

Xu H, Manivannan A, Liversidge J, Sharp PF, Forrester JV, and Crane IJ. 2002. J. Leukoc. Biol. 72:1133-1141. (in vivo functional assays, induction of apoptosis)

Si-Tahar M, Sitaraman S, Shibahara T, and Madara JL. 2001. Am. J. Physiol. Cell Physiol. 280:C423-C432. (in vitro functional assays, Western Blot)

Gene SymbolCD44, CD44
Gene Full NameCD44 molecule (Indian blood group)
Alias SymbolsPgp, HERM, Ly-2, Ly-24, Pgp-1, HERMES, AU023126, AW121933, AW146109
NCBI Gene Id12505; 960
Protein NameCD44 antigen
Description of TargetThe protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Uniprot IDP16070, P15379
Protein Accession #NP_000601.3
Nucleotide Accession #NM_000610.3
  1. What is the species homology for "CD44/CD44 Antibody : FITC (OATA00211)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Baboon, Canine, Chimpanzee, Cynomolgus, Equine, Feline, Rhesus, Swine".

  2. How long will it take to receive "CD44/CD44 Antibody : FITC (OATA00211)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "CD44/CD44 Antibody : FITC (OATA00211)" provided in?

    This item is provided in "Liquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CD44/CD44 Antibody : FITC (OATA00211)"?

    This target may also be called "Pgp, HERM, Ly-2, Ly-24, Pgp-1, HERMES, AU023126, AW121933, AW146109" in publications.

  5. What is the shipping cost for "CD44/CD44 Antibody : FITC (OATA00211)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CD44/CD44 Antibody : FITC (OATA00211)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CD44/CD44 Antibody : FITC (OATA00211)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CD44/CD44 Antibody : FITC (OATA00211)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CD44, CD44"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CD44, CD44"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CD44, CD44"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CD44, CD44"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CD44, CD44"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CD44, CD44"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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