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Datasheets/Manuals | Printable datasheet for CD4 Antibody (OAPB01358) (OAPB01358) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid. CD4 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Monoclonal |
Host | CD4 monoclonal antibody was raised in mouse. Please use anti-mouse secondary antibodies. |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | CD4 monoclonal antibody can be stored at 4C, stable for one year. |
Immunogen | Mouse monoclonal CD4 antibody was raised against a 193 amino acid recombinant protein from near the amino terminus of human CD4. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human; Mouse; Rat |
Concentration | 1 mg/ml |
Application Info | CD4 antibody can be used for detection of CD4 by Western blot at 0.5 – 1 ug/mL. (Optimal dilution should be determined by user) |
Reference | Bowers K, Pitcher C, and Marsh M. CD4Â : a co-receptor in the immune response and HIV infection. Int. J. Biochem. Cell Biol. 1997; 29Â :871-5.;Arthos J, Deen KC, Chaikin MA, et al. Identification of the residues in human CD4 critical for the binding of HIV. Cell 1989; 57:469-81. ; |
Gene Symbol | CD4 |
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Gene Full Name | CD4 molecule |
Alias Symbols | CD4 antigen (p55);CD4 receptor;CD4mut;IMD79;OKT4D;T-cell surface antigen T4/Leu-3;T-cell surface glycoprotein CD4. |
NCBI Gene Id | 920 |
Protein Name | T-cell surface glycoprotein CD4|T-cell surface glycoprotein CD4 isoform 1 precursor [Homo sapiens] |
Description of Target | Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages. |
Uniprot ID | P01730 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_000607 |
Molecular Weight | Predicted: 51kD Observed: 51-57 kD (Post-modyfication: 2-4 N-linked glycosylations) |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CD4 Antibody (OAPB01358)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "CD4 Antibody (OAPB01358)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "CD4 Antibody (OAPB01358)" provided in?
This item is provided in "Liquid. CD4 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CD4 Antibody (OAPB01358)"?
This target may also be called "CD4 antigen (p55);CD4 receptor;CD4mut;IMD79;OKT4D;T-cell surface antigen T4/Leu-3;T-cell surface glycoprotein CD4." in publications.
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What is the shipping cost for "CD4 Antibody (OAPB01358)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CD4 Antibody (OAPB01358)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CD4 Antibody (OAPB01358)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "Predicted: 51kD Observed: 51-57 kD (Post-modyfication: 2-4 N-linked glycosylations)".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CD4 Antibody (OAPB01358)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CD4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CD4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CD4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CD4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CD4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CD4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.