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CD3E cDNA (ANA10561)

1ug
$189.00
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Gene Symbol:
CD3E
NCBI Gene Id:
916
Description of Target:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Nucleotide Accession #:
BC049847
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CD3E.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CD3E.
Tag:
None
Protein Interactions:
UBC; CSK; ZAP70; SNTA1; PTPN22; PIK3R2; PIK3R1; LAT; LCK; CD38; CD247; CD3G; TRAT1; NCK2; UNC119; SHC1; NCK1; SYK; CD3D; NCL; CD79B; TOP2B; CD3EAP; JAK3;
Reconstitution and Storage:
Centrifuge the vials after receiving and add 5 μl ddH2O
Datasheets/Manuals:
Printable datasheet for anti-CD3E (ANA10561) antibody

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