CD300LF Antibody - N-terminal region (OAAB06549)

Catalog No: OAAB06549

Size:400ul

Western blot analysis of CLM1 Antibody (N-term) in K562 cell lysates (35ug/lane). CLM1 (arrow) was detected using the purified Pab.

CLM1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CLM1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: WB, IHC-P, FC
  Function: Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation.
  Cellular Location: Cell membrane; Single-pass type I membrane protein
  Tissue Location: Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This CLM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human CLM1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50

Target Info

• Gene Symbol: CD300LF
• Alias Symbols: CLM1, NKIR, CLM-1, IREM1, LMIR3, CD300f, IREM-1, IgSF13
• NCBI Gene Id: 146722
• Protein Name: CMRF35-like molecule 1
• Description of Target: CLM1 is an inhibitory receptor of the Ig superfamily expressed on myeloid cells. It mediates negative regulatory signals by recruiting SHP1 (PTPN6; MIM 176883) or SHIP.
• Uniprot ID: Q8TDQ1
• Protein Accession #: NP_620587.2
• Molecular Weight: 32 kDa