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CD271 Antibody - C-terminal region (OAAB08817)

400ul
$390.00
In Stock
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Gene Symbol:
NGFR
NCBI Gene Id:
4804
Protein Name:
Tumor necrosis factor receptor superfamily member 16
Swissprot Id:
P08138
Protein Accession #:
NP_002498.1
Alias Symbols:
NGFR, TNFRSF16, Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, p75 ICD, CD_antigen=CD271, Flags: Precursor
Replacement Item:
This antibody may replace item sc-13577, HPA004765
Description of Target:
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Molecular Weight:
45183 Da
Host:
Rabbit
Clonality:
Polyclonal
Application:
WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NGFR.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NGFR.
Immunogen:
This CD271 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-380 amino acids from the C-terminal region of human CD271.
Predicted Species Reactivity:
Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Human; Mouse; Rat
Product Format:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals:
Printable datasheet for OAAB08817
Sample Type Confirmation:

NGFR is strongly supported by BioGPS gene expression data to be expressed in MDA-MB435

Isotype:
Ig
Application Info:
WB: 1:1000
IHC-P: 1:10~50
Additional Information:
Precautions: CD271 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
:::
Function: Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells
:::
Cellular Location: Membrane; Single-pass type I membrane protein

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