CD271 Antibody - C-terminal region (OAAB08817)

Catalog No: OAAB08817

Size:400ul

CD271 Antibody (C-term) (Cat. #OAAB08817) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CD271 antibody detected the CD271 protein (arrow).

NGFR is strongly supported by BioGPS gene expression data to be expressed in MDA-MB435

CD271 Antibody (C-term) (Cat. #OAAB08817)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD271 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC
• Additional Information: Precautions: CD271 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells
  Cellular Location: Membrane; Single-pass type I membrane protein
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This CD271 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-380 amino acids from the C-terminal region of human CD271.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  NGFR is strongly supported by BioGPS gene expression data to be expressed in MDA-MB435

• Application Info: WB: 1:1000
  IHC-P: 1:10~50

Target Info

• Gene Symbol: NGFR
• Alias Symbols: CD271, p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR
• NCBI Gene Id: 4804
• Protein Name: Tumor necrosis factor receptor superfamily member 16
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: P08138
• Protein Accession #: NP_002498.1
• Molecular Weight: 45183 Da