Search Antibody, Protein, and ELISA Kit Solutions

CD27 Antibody (OABF00993)

100 ul
$349.00
In Stock
Request Bulk Order Quote

Conjugation Options

OABF00993-FITC Conjugated

OABF00993-HRP Conjugated

OABF00993-Biotin Conjugated

Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Conjugation:
Unconjugated
Application:
WB, IHC-P
Additional Information:
Subcellular location: Cytoplasm
Reconstitution and Storage:
Store at -20C for 12 months.
Replacement Item:
This antibody may replace item sc-1740 from Santa Cruz Biotechnology.
Immunogen:
KLH conjugated synthetic peptide derived from human CD27
Purification:
Purified by Protein A.
Concentration:
1ug/ul
Datasheets/Manuals:
Printable datasheet for OABF00993
Application Info:
WB: 1:100 - 1000
IHC-P: : 1:100 - 500
Gene Symbol:
CD27
Official Gene Full Name:
CD27 molecule
Alias Symbols:
T14, S152, Tp55, TNFRSF7, S152. LPFS2,
NCBI Gene Id:
939
Description of Target:
CD Marcker CD27 is a member of the tumor necrosis factor (TNF) receptor superfamily. CD40 and CD30 are also members of the TNF receptor superfamily. The TNF superfamily members are known for the regulation of cell proliferation and death. In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes. High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors. CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals. CD27 is a membranebound receptor, but a soluble form of CD27 is also produced. Soluble CD27 is found in body fluids and can be used to monitor local and systemic immune activation. In addition, elevated serum concentrations of soluble CD27 are found in patients with B cell malignancies and soluble CD27 levels strongly correlate with tumor load.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CD27.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CD27.

Product Reviews

Protocol:
Tips Information:

Tell us what you think about this item!

Write A Review
    Please, wait...