Size:100 ul
$320.00
Discontinued
SKU
OAAB20992
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CD27 Antibody (OAAB20992)

Catalog#: OAAB20992
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More Information
Predicted Species Reactivity Human, Mouse
Product Format Liquid
Clonality Polyclonal
Isotype Rabbit IgG
Host Rabbit
Application WB
Additional Information Function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Reconstitution and Storage Store at 2-8C for up to 6 months. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-1740 from Santa Cruz Biotechnology.
Predicted Homology Based on Immunogen Sequence Human, Mouse
Concentration 1 mg/mL
Datasheets/Manuals Printable datasheet for anti-CD27 (OAAB20992) antibody
Preservative 0.02% Sodium Azide and 50% glycerol
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Target Reference Camerini D.,et al.J. Immunol. 147:3165-3169(1991).
Loenen W.A.,et al.J. Immunol. 149:3937-3943(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
Gene Symbol CD27
Official Gene Full Name CD27 molecule
Alias Symbols T14, S152, Tp55, TNFRSF7, S152. LPFS2
NCBI Gene Id 939
Description of Target The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Swissprot Id P26842
Protein Accession # NP_001233.1
Nucleotide Accession # NM_001242.4
Molecular Weight 29 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express CD27.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express CD27.
  1. What is the species homology for "CD27 Antibody (OAAB20992)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "CD27 Antibody (OAAB20992)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "CD27 Antibody (OAAB20992)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CD27 Antibody (OAAB20992)"?

    This target may also be called "T14, S152, Tp55, TNFRSF7, S152. LPFS2" in publications.

  5. What is the shipping cost for "CD27 Antibody (OAAB20992)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CD27 Antibody (OAAB20992)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CD27 Antibody (OAAB20992)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "29 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CD27 Antibody (OAAB20992)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "CD27"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CD27"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CD27"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CD27"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CD27"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CD27"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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