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Catalog No: OATA00587
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OATA00587
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Datasheets/ManualsPrintable datasheet for OATA00587
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityChimpanzee
Product FormatLiquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2
ClonalityMonoclonal
CloneUCHT1
IsotypeMouse IgG1, kappa
HostMouse
ApplicationFC
::Excitation Laser: Violet (405 nm)
::Emmision: 450 nm
Reconstitution and Storage2-8C protected from light
SpecificityCD3
Application InfoThis antibody preparation has been pre-titrated and quality-tested for flow cytometry using an appropriate cell type. The antibody has been diluted for use at 5 uL per test, defined as the amount of antibody that will stain a cell sample in a final volume of approximately 100 uL. The number of cells within a sample should be determined empirically, but typically ranges between 1x10e5 to 1x10e8 cells.violetFluor 450 dye is excited by the violet (405 nm) laser and has a peak emission of 450 nm. The most common band pass filters for this dye are 440/40 or 450/50. violetFluor 450 can be used as an alternative for Pacific Blue, BD Horizon V450 or eFluor 450.
Reference

Harris SJ, Parry RV, Foster JG, Blunt MD, Wang A, Marelli-Berg F, Westwick J, and Ward SG. Apr. 2011. J. Immunol. 186: 4936-4945. (in vitro activation)

Beriou G, Bradshaw EM, Lozano E, Costantino CM, Hastings WD, Orban T, Elyaman W, Khoury SJ, Kuchroo VK, Baecher-Allan C, and Hafler DA. 2010. J. Immunol. 185: 46-54. (in vitro activation)

Soto PC, Stein LL, Hurtado-Ziola N, Hedrick SM, and Varki A. 2010. J. Immunol. 184: 4185-4195. (Flow cytometry - Chimpanzee)

Edelbauer M, Datta D, Vos IHC, Basu A, Stack MP, Reinders MEJ, Sho M, Calzadilla K, Ganze P, and Briscoe DM. 2010. Blood. 116:1980-1989. (Immunohistochemistry - acetone fixed, frozen sections; Immunofluoresence microscopy)

Varghese JC and Kane KP. 2008. J. Immunol. 181: 6002-6009. (in vitro activation)

Mack CL, Tucker RM, Sokol RJ, Darrer FM, Kotzin BL, Whitington PF and Miller SD. 2004. Pediatr. Res. 56(1):79-87. (Immunohistochemistry - frozen tissue)

Sakkas LI, Scanzello C, Johanson N, Burkholder J, Mitra A, Salgame P, Katsetos CD, and Platsoucas CD. 1998. Clin. Diagn. Lab. Immun. 5:430. (Immunohistochemistry - acetone fixed, frozen sections)

Salmeron A, Sanchez-Madrid F, Ursa MA, Fresno M, and Alarcon B. 1991. J. Immunol. 147:3047-3052. (Immunoprecipitation)

Van Dongen JJ, Krissansen GW, Wolvers-Tettero IL, Comans-Bitter WM, Adriaansen HJ, Hooijkaas H, van Wering ER, and Terhorst C. 1988. Blood. 71: 603-612. (Western Blot)

Gene SymbolCD247, CD3D, CD3E, CD3G
Gene Full NameCD247 molecule
Alias SymbolsT3D, IMD19, CD3-DELTA
NCBI Gene Id915; 916; 917; 919
Protein NameT-cell surface glycoprotein CD3 zeta chain
Description of TargetThe protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Uniprot IDP20963, A8MVP6, P07766, P09693
Protein Accession #NP_000725.1
Nucleotide Accession #NM_000734.3
  1. What is the species homology for "CD247/CD3D/CD3E/CD3G Antibody (OATA00587)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Chimpanzee".

  2. How long will it take to receive "CD247/CD3D/CD3E/CD3G Antibody (OATA00587)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "CD247/CD3D/CD3E/CD3G Antibody (OATA00587)" provided in?

    This item is provided in "Liquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CD247/CD3D/CD3E/CD3G Antibody (OATA00587)"?

    This target may also be called "T3D, IMD19, CD3-DELTA" in publications.

  5. What is the shipping cost for "CD247/CD3D/CD3E/CD3G Antibody (OATA00587)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CD247/CD3D/CD3E/CD3G Antibody (OATA00587)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CD247/CD3D/CD3E/CD3G Antibody (OATA00587)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CD247/CD3D/CD3E/CD3G Antibody (OATA00587)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CD247, CD3D, CD3E, CD3G"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CD247, CD3D, CD3E, CD3G"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CD247, CD3D, CD3E, CD3G"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CD247, CD3D, CD3E, CD3G"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CD247, CD3D, CD3E, CD3G"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CD247, CD3D, CD3E, CD3G"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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