CD1B Antibody (OAEE00134)

Catalog No: OAEE00134

Size:100UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Clonality: Monoclonal
• Clone: SN13
• Isotype: IgG1
• Host: Mouse
• Application: Flow cytometry|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Immunoprecipitation
• Reconstitution and Storage: 2°C to 8°C
• Immunogen: A cell membrane antigen preparation that was isolated from normal human thymocytes
• Purification: Purified
• Concentration: 1 mg/ml
• Specificity: The mouse monoclonal antibody SN13 (also known as K5-1B8) recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells.
• Formulation: Purified
• Purity: > 95% (by SDS-PAGE)
• Storage Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
• Reference: Hayes SM, Knight KL: Group 1 CD1 genes in rabbit. J Immunol. 2001 Jan 1;166(1):403-10.
  Tentori L, Graziani G, Porcelli SA, Sugita M, Brenner MB, Madaio R, Bonmassar E, Giuliani A, Aquino A: Rifampin increases cytokine-induced expression of the CD1b molecule in human peripheral blood monocytes. Antimicrob Agents Chemother. 1998 Mar;42(3):550-4.
  Giuliani A, Prete SP, Graziani G, Aquino A, Balduzzi A, Sugita M, Brenner MB, Iona E, Fattorini L, Orefici G, Porcelli SA, Bonmassar E: Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells. Infect Immun. 2001 Dec;69(12):7461-70.
  Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997).
  

Target Info

• Gene Symbol: CD1B
• Gene Full Name: CD1b molecule
• Alias Symbols: CD1;CD1A;CD1B antigen, b polypeptide;cortical thymocyte antigen CD1B;differentiation antigen CD1-alpha-3;R1;T-cell surface glycoprotein CD1b.
• NCBI Gene Id: 910
• Protein Name: T-cell surface glycoprotein CD1b
• Description of Target: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
• Uniprot ID: P29016
• Protein Accession #: NP_001755.1
• Nucleotide Accession #: NM_001764.2