Size:100 ug
$269.00
Discontinued
SKU
OABB00229
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CD133 Polyclonal Antibody (OABB00229)

Catalog#: OABB00229
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Predicted Species Reactivity Human, Mouse, Rat
Product Format Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application WB, IHC-P
Reconstitution and Storage Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time. Avoid repeated freezing and thawing.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminal of human CD133 (171-191aa, NHQVRTRIKRSRKLADSNFKD).
Purification Immunogen affinity purified.
Datasheets/Manuals Printable datasheet for OABB00229
Specificity No cross reactivity with other proteins.
Application Info WB: 0.1-0.5ug/ml; Tested Species: Human
IHC-P: 0.5-1ug/ml; Antigen Retrieval: Enzyme Digestion. Tested Species: Human, Rat
Target Reference 1. Corbeil D, Fargeas C, Huttner W (2001). "Rat prominin, like its mouse and human orthologues, is a pentaspan membrane glycoprotein". Biochem Biophys Res Commun 285 (4): 939-44.
2. Maw, M. A.; Corbeil, D.. Koch, J.; Hellwig, A.; Wilson-Wheeler, J. C.; Bridges, R. J, Kumaramanickavel, G.; John, S.; Nancarrow, D.,Roper, K., Weigmann, A,Huttner, W. B.; Denton, M. J. : A frameshift mutation in prominin (mouse)-like 1 causes human retinal degeneration. Hum. Molec. Genet. 9: 27-34, 2000.
3. Corbeil D, Roper K, Hellwig A, Tavian M, Miraglia S, Watt S, Simmons P, Peault B, Buck D, Huttner W (2000). "The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions". J Biol Chem 275 (8): 5512-20.
4. Shmelkov S, St Clair R, Lyden D, Rafii S (2005). "AC133/CD133/Prominin-1". Int J Biochem Cell Biol 37 (4): 715-9.
Publications

Maleklou, N; Allameh, A; Kazemi, B; Targeted delivery of vitamin D3-loaded nanoparticles to C6 glioma cell line increased resistance to doxorubicin, epirubicin, and docetaxel in vitro. 52, 989-1000 (2016). WB, IHC-P, Human, Mouse, Rat 27503515

Gene Symbol PROM1
Official Gene Full Name Prominin-1
Alias Symbols Antigen AC133, Prominin-like protein 1, CD_antigen=CD133
Description of Target CD133, is a glycoprotein also known in humans and rodents as Prominin 1 (PROM1).1 It is the founding member of pentaspan transmembrane glycoproteins (5-transmembrane, 5-TM), which specifically localizes to cellular protrusions. The gene of CD133 is located in 4p15.3. And most of the CD133 gene is contained in 23 exons distributed over more than 50 kb of genomic sequence.2 CD133 is expressed in hematopoietic stem cells, endothelial progenitor cells, glioblastomas, neuronal and glial stem cells and some other cell types.3,4
Swissprot Id O43490
  1. What is the species homology for "CD133 Polyclonal Antibody (OABB00229)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "CD133 Polyclonal Antibody (OABB00229)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "CD133 Polyclonal Antibody (OABB00229)" provided in?

    This item is provided in "Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CD133 Polyclonal Antibody (OABB00229)"?

    This target may also be called "Antigen AC133, Prominin-like protein 1, CD_antigen=CD133" in publications.

  5. What is the shipping cost for "CD133 Polyclonal Antibody (OABB00229)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CD133 Polyclonal Antibody (OABB00229)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CD133 Polyclonal Antibody (OABB00229)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CD133 Polyclonal Antibody (OABB00229)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "PROM1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PROM1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PROM1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PROM1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PROM1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PROM1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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