Catalog No: OAAB05403
Size:400ul
Price: $389.00
SKU
OAAB05403
Availability: Domestic: within 1 week delivery | International: 1 week
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CCR3 Antibody - middle region (OAAB05403)

CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
Datasheets/ManualsPrintable datasheet for anti-CCR3 antibody - OAAB05403
Product Info
Predicted Species ReactivityHuman, Monkey
Product FormatLiquid PBS with 0.09% (W/V) sodium azide.
ClonalityPolyclonal
IsotypeRabbit Ig
HostRabbit
ApplicationWB, FC, ELISA
Additional InformationCellular Location: Cell membrane; Multi-pass membrane protein.
Tissue Location: In eosinophils as well as trace amounts in neutrophils and monocytes.
Reconstitution and StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis CCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-318 amino acids from the Central region of human CCR3.
PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
Predicted Homology Based on Immunogen SequenceHuman
Concentration0.5 mg/ml
Application InfoWB: 1:1000
FC: 1:10~50
Other Applications Image 1 DataCCR3 Antibody (Center) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Publications

Simvastatin Inhibits IL-5-Induced Chemotaxis and CCR3 Expression of HL-60-Derived and Human Primary Eosinophils. PLoS ONE. 11, e0157186 (2016). 27275740

Gene SymbolCCR3
Alias SymbolsCKR3, CD193, CKR 3, CMKBR3, C C CKR3, CC-CKR-3
NCBI Gene Id1232
Protein NameC-C chemokine receptor type 3
Uniprot IDP51677
Protein Accession #NP_001828.1
Molecular Weight41 kDa
  1. What is the species homology for "CCR3 Antibody - middle region (OAAB05403)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Monkey".

  2. How long will it take to receive "CCR3 Antibody - middle region (OAAB05403)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "CCR3 Antibody - middle region (OAAB05403)" provided in?

    This item is provided in "Liquid PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CCR3 Antibody - middle region (OAAB05403)"?

    This target may also be called "CKR3, CD193, CKR 3, CMKBR3, C C CKR3, CC-CKR-3" in publications.

  5. What is the shipping cost for "CCR3 Antibody - middle region (OAAB05403)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CCR3 Antibody - middle region (OAAB05403)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CCR3 Antibody - middle region (OAAB05403)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "41 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CCR3 Antibody - middle region (OAAB05403)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CCR3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CCR3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CCR3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CCR3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CCR3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CCR3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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