CCR2 Antibody - N-terminal region (OASA06081)

Catalog No: OASA06081 (Formerly GWB-DD17AF)

Size:0.1mg

Paraffin embedded human spleen stained with Goat anti Human CD192 (N-Terminal) -

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified IgG - liquid
• Clonality: Polyclonal
• Isotype: Polyclonal IgG
• Host: Goat
• Application: IHC-FFPE, WB
• Additional Information: Histology Positive Control Tissue: Spleen
  Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
  0.1% Bovine Serum Albumin
  Antiserum Preparation: Antiserum to human CD192 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
  Approx Protein Conc: IgG concentration 1.0mg/ml
  Buffer Solutions: 10mM KHPO4, 140mM NaCl, pH7.2
• Reconstitution and Storage: Store at +4^oC or at -20^oC if preferred.
  Storage in frost-free freezers is not recommended.
  This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
  
• Immunogen: The immunogen for anti-CCR2 antibody: synthetic peptide C-GEEVTTFFDYDYGAPCHKFDVKQ corresponding to amino acids 17-39 within the N-terminal region of human CD192.
• Predicted Homology Based on Immunogen Sequence: Human
• Specificity: CD192
• Application Info: ELISA : This product is suitable for use in indirect ELISA applications.
• Application Data: Application #1: Paraffin embedded human spleen stained with Goat anti Human CD192 (N-Terminal) -
• Publications:

  Bhangoo, S. et al. Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of peripheral nociceptors. Mol. Pain 3, 38 (2007). 18076762

  Bhangoo, S. K., Ripsch, M. S., Buchanan, D. J., Miller, R. J. & White, F. A. Increased chemokine signaling in a model of HIV1-associated peripheral neuropathy. Mol. Pain 5, 48 (2009). 19674450

  Jeon, S.-M., Sung, J.-K. & Cho, H.-J. Expression of monocyte chemoattractant protein-1 and its induction by tumor necrosis factor receptor 1 in sensory neurons in the ventral rhizotomy model of neuropathic pain. Neuroscience 190, 354-66 (2011). 21712071

Target Info

• Gene Symbol: CCR2
• Alias Symbols: CKR2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2
• NCBI Gene Id: 1231
• Protein Name: C-C chemokine receptor type 2
• Description of Target: GOAT ANTI HUMAN CD192 (N-TERMINAL)
  
• Uniprot ID: P41597
• Protein Accession #: NP_001116513.2
• Protein Size (# AA): 374