Size:100 ul
Special Price $229.00 Regular Price $289.00
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ARP58409_P050
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Conjugation Options

ARP58409_P050-FITC Conjugated

ARP58409_P050-HRP Conjugated

ARP58409_P050-Biotin Conjugated

CCR2 Antibody - middle region (ARP58409_P050)

Catalog#: ARP58409_P050
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Human, Pig, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-30032 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CCR2
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Human: 100%; Pig: 93%; Rabbit: 93%; Rat: 93%
Complete computational species homology data Anti-CCR2 (ARP58409_P050)
Peptide Sequence Synthetic peptide located within the following region: LIMVICYSGILKTLLRCRNEKKRHRAVRVIFTIMIVYFLFWTPYNIVILL
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-CCR2 (ARP58409_P050) antibody is Catalog # AAP58409 (Previous Catalog # AAPP34424)
Datasheets/Manuals Printable datasheet for anti-CCR2 (ARP58409_P050) antibody
Target Reference Hendrickson,S.L., (2008) J. Acquir. Immune Defic. Syndr. 48 (3), 263-271
Publications

Liang, X., Li, H. & Li, S. A novel network pharmacology approach to analyse traditional herbal formulae: the Liu-Wei-Di-Huang pill as a case study. Mol. Biosyst. 10, 1014-22 (2014). WB, Human, Pig, Rabbit, Rat 24492828

Gene Symbol CCR2
Official Gene Full Name Chemokine (C-C motif) receptor 2
Alias Symbols CC-CKR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R
NCBI Gene Id 1231
Protein Name C-C chemokine receptor type 2
Description of Target This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
Swissprot Id P41597
Protein Accession # NP_000638
Nucleotide Accession # NM_000647
Protein Size (# AA) 374
Molecular Weight 42kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express CCR2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express CCR2.
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