Size:100 ul
Special Price $229.00 Regular Price $289.00
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ARP58410_P050
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Conjugation Options

ARP58410_P050-FITC Conjugated

ARP58410_P050-HRP Conjugated

ARP58410_P050-Biotin Conjugated

CCR2 Antibody - C-terminal region (ARP58410_P050)

Catalog#: ARP58410_P050
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Horse, Human
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-30032 from Santa Cruz Biotechnology.
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 79%; Dog: 79%; Horse: 79%; Human: 100%
Complete computational species homology data Anti-CCR2 (ARP58410_P050)
Peptide Sequence Synthetic peptide located within the following region: FTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGM
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-CCR2 (ARP58410_P050) antibody is Catalog # AAP58410
Datasheets/Manuals Printable datasheet for anti-CCR2 (ARP58410_P050) antibody
Publications

Murakami, K; Maeda, S; Yonezawa, T; Matsuki, N; CC chemokine ligand 2 and CXC chemokine ligand 8 as neutrophil chemoattractant factors in canine idiopathic polyarthritis. 182, 52-58 (2016). WB, Cow, Dog, Horse, Human 27863550

Gene Symbol CCR2
Official Gene Full Name Chemokine (C-C motif) receptor 2
Alias Symbols CKR2, CCR-2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2
NCBI Gene Id 1231
Protein Name C-C chemokine receptor type 2
Description of Target This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.
Swissprot Id P41597
Protein Accession # NP_000638
Nucleotide Accession # NM_000647
Protein Size (# AA) 374
Molecular Weight 42kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express CCR2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express CCR2.
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