CCNT2 Antibody (OAGA00937)

Catalog No: OAGA00937

Size:100 ul

Sample (30 ug of whole cell lysate)
A: Hep G2
7.5% SDS PAGE
OAGA00937 diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded H1299 Xenograft, using cyclin T2(OAGA00937) antibody at 1:100 dilution.

Immunofluorescence analysis of paraformaldehyde-fixed A431, using cyclin T2(OAGA00937) antibody at 1:200 dilution.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7). 0.01% Thimerosal was added as a preservative
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: ICC, IF, IHC-FFPE, WB
  Positive Controls:n293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
  Cellular Localization: Nucleus
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant fragment corresponding to a region within amino acids 497 and 730 of cyclin T2. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Predicted Homology Based on Immunogen Sequence: Rat (80%), Bovine (95%)
• Concentration: 0.51 mg/ml
• Application Info: ICC/IF: 1:100~1000
  IHC-FFPE: 1:100~1000
  WB: 1:500~3000

Target Info

• Gene Symbol: CCNT2
• Gene Full Name: Cyclin-T2
• Alias Symbols: CYCT2
• NCBI Gene Id: 905
• Protein Name: Cyclin-T2
• Description of Target: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. Two alternatively spliced transcript variants, which encode distinct isoforms, have been described.
• Uniprot ID: O60583
• Protein Accession #: NP_001232.1
• Molecular Weight: 81 kDa