CCNE2 Antibody (Phospho-Thr392) (OASG01945)

Catalog No: OASG01945

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: ELISA, IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human Cyclin E2 around the phosphorylation site of T392. Location: 330-410aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Thr392
• Specificity: Phospho-Cyclin E2 (T392) Polyclonal Antibody detects endogenous levels of Cyclin E2 protein only when phosphorylated at T392.
• Application Info: IF 1:200-1:1000; ELISA 1:10000;

Target Info

• Gene Symbol: CCNE2
• Gene Full Name: cyclin E2
• Alias Symbols: CYCE2
• NCBI Gene Id: 9134; 12448;
• Description of Target: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.
• Uniprot ID: O96020, Q9Z238
• Molecular Weight: 46 kDa