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Catalog No: AVARP03038_P050
Price: $0.00
SKU
AVARP03038_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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Datasheets/ManualsPrintable datasheet for anti-CCND3 (AVARP03038_P050) antibody
Product Info
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Sheep
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human CCND3
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Sheep: 100%
Peptide SequenceSynthetic peptide located within the following region: CQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
Concentration0.5 mg/ml
Blocking PeptideFor anti-CCND3 (AVARP03038_P050) antibody is Catalog # AAP30245 (Previous Catalog # AAPP00415)
Sample Type Confirmation

CCND3 is supported by BioGPS gene expression data to be expressed in Jurkat

ReferencePruneri,G., et al., (2004) Int. J. Cancer 112 (1), 71-77
Publications

Discovery of Human-Similar Gene Fusions in Canine Cancers. Cancer Res. 77, 5721-5727 (2017). 28883003

Description
Gene SymbolCCND3
Gene Full NameCyclin D3
NCBI Gene Id896
Protein NameG1/S-specific cyclin-D3
Description of TargetCCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.
Uniprot IDP30281
Protein Accession #NP_001751
Nucleotide Accession #NM_001760
Protein Size (# AA)292
Molecular Weight33kDa
Protein InteractionsPOLR3GL; TFIP11; CDKN1A; CDK6; CDK4; CDK5; MCM10; CDKN1B; CDK2; CDK11B; FAS; SIL1; EIF3K; ATF5; VDR; MAPK6; NME1; MYB; GC; ETV1; RBL2; POLD1; CDK14; APP; RB1; UBC; PPP1CC; PPP1CB; PPP1CA; NCOA2; MAF1; NPDC1; DMTF1; CRABP2; RARA; DTNBP1; AKAP8; EFEMP2; CAS
  1. What is the species homology for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Sheep".

  2. How long will it take to receive "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CCND3 Antibody - C-terminal region (AVARP03038_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "33kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CCND3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CCND3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CCND3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CCND3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CCND3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CCND3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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