CCL5 Recombinant Protein (OPCD06595)

Catalog No: OPCD06595

CCL5 Recombinant Protein (OPCD06595) using SDS-PAGE

CCL5 Recombinant Protein (OPCD06595) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Canis lupus|Dog
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser24-Ser91
  Subcellular Location: Secreted.
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: CCL5
• Gene Full Name: C-C motif chemokine ligand 5
• Alias Symbols: C-C motif chemokine 5;RANTES;small-inducible cytokine A5;T-cell-specific protein RANTES.
• NCBI Gene Id: 403522
• Protein Name: C-C motif chemokine 5
• Description of Target: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.
• Uniprot ID: Q8HYS0
• Protein Accession #: NP_001003010.1
• Nucleotide Accession #: NM_001003010.2
• Protein Size (# AA): Ser24~Ser91
• Molecular Weight: 17kDa