CCL19 Recombinant Antibody [3A12] (OACA12741)

Catalog No: OACA12741

Size:100UL

IHC image of OACA12741 diluted at 1:155 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of OACA12741 diluted at 1:155 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Recombinant Monoclonal
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay,
  Immunohistochemistry
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: A synthesized peptide derived from human CCL19
• Purification: Affinity Purified

Target Info

• Gene Symbol: CCL19
• Gene Full Name: C-C motif chemokine ligand 19
• Alias Symbols: beta chemokine exodus-3;Beta-chemokine exodus-3;CC chemokine ligand 19;C-C motif chemokine 19;chemokine (C-C motif) ligand 19;CK beta-11;CKb11;EBI1-ligand chemokine;ELC;epstein-Barr virus-induced molecule 1 ligand chemokine;exodus-3;Macrophage inflammatory protein 3 beta;macrophage inflammatory protein 3-beta;MIP-3b;MIP3B;MIP-3-beta;SCYA19;small inducible cytokine subfamily A (Cys-Cys), member 19;small-inducible cytokine A19.
• NCBI Gene Id: 6363
• Protein Name: C-C motif chemokine 19
• Description of Target: May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
• Uniprot ID: Q99731