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CBX1 Antibody (OADC00153)

50ug
$319.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. Provided in PBS containing 0.05% azide and 0.05% ProClin 300.
Clonality:
Polyclonal
Host:
Rabbit
Conjugation:
Unconjugated
Application:
CHIP, WB, IF
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-10212 from Santa Cruz Biotechnology.
Purification:
Affinity purified
Concentration:
2 mg/mL
Datasheets/Manuals:
Printable datasheet for anti-CBX1 (OADC00153) antibody
Preservative:
0.05% Sodium Azide and 0.05% ProClin 300.
Specificity:
Polyclonal antibody raised in rabbit against human HP1 β (Heterochromatin protein 1 homolog beta), using the full length recombinant GST tagged protein. The antibody also recognizes the α and γ isoforms.
Application Info:
CHIP: 4 ug/CHIP
Western Blotting: 1:1,000
Immunofluorescence: 1:500
Gene Symbol:
CBX1
Official Gene Full Name:
chromobox 1
Alias Symbols:
CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta
NCBI Gene Id:
10951; 23468; 11335
Protein Name:
chromobox protein homolog 1
Description of Target:
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Swissprot Id:
P45973
Protein Accession #:
NP_001120793.1
Nucleotide Accession #:
NM_001127321.1
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CBX1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CBX1.

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