CBR1 Recombinant Protein (OPCD00838)

Catalog No: OPCD00838

CBR1 Recombinant Protein (OPCD00838) using SDS-PAGE

CBR1 Recombinant Protein (OPCD00838) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser2-Trp277
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: CBR1
• Gene Full Name: carbonyl reductase 1
• Alias Symbols: 15-hydroxyprostaglandin dehydrogenase;15-hydroxyprostaglandin dehydrogenase [NADP(+)];20-beta-hydroxysteroid dehydrogenase;carbonyl reductase (NADPH) 1;carbonyl reductase [NADPH] 1;CBR;epididymis secretory sperm binding protein;hCBR1;NADPH-dependent carbonyl reductase 1;PG-9-KR;prostaglandin 9-ketoreductase;prostaglandin-E(2) 9-reductase;SDR21C1;short chain dehydrogenase/reductase family 21C member 1.
• NCBI Gene Id: 873
• Protein Name: Carbonyl reductase [NADPH] 1
• Description of Target: NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
• Uniprot ID: P16152
• Protein Accession #: NP_001273718.1
• Nucleotide Accession #: NM_001286789.1
• Protein Size (# AA): Ser2~Trp277
• Molecular Weight: 35kDa