Size:100 ul
$329.00
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SKU
OAGA00723
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CBFA2T2 Antibody (OAGA00723)

Catalog#: OAGA00723
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human
Product Format Liquid
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application ICC, IF, WB
Additional Information Background: In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. [provided by RefSeq]
:: Positive Controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
:: Cellular Localization: Nucleus
Reconstitution and Storage Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item This antibody may replace item sc-390114 from Santa Cruz Biotechnology.
Immunogen Recombinant fragment corresponding to a region within amino acids 401 and 604 of CBFA2T2 (Uniprot ID#O43439)
Purification Purified by antigen-affinity chromatography.
Concentration 1 mg/ml
Datasheets/Manuals Printable datasheet for anti-CBFA2T2 antibody - OAGA00723
Application Info Suggested starting dilutions are as follows: WB: 1:500-1:3000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol CBFA2T2
Official Gene Full Name Protein CBFA2T2
Alias Symbols DKFZp313F2116 antibody, EHT antibody, MTGR1 antibody, ZMYND3 antibody, p85 antibody, CBFA2T2 antibody, myeloid translocation gene-related protein 1 antibody, MTG8-like protein antibody, MTG8-related protein 1 antibody, ETO homolog on chromosome 20 antibod
NCBI Gene Id 9139
Protein Name Protein CBFA2T2
Swissprot Id O43439
Protein Accession # NP_001028171.1
Molecular Weight 67 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express CBFA2T2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express CBFA2T2.
  1. What is the species homology for "CBFA2T2 Antibody (OAGA00723)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "CBFA2T2 Antibody (OAGA00723)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "CBFA2T2 Antibody (OAGA00723)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CBFA2T2 Antibody (OAGA00723)"?

    This target may also be called "DKFZp313F2116 antibody, EHT antibody, MTGR1 antibody, ZMYND3 antibody, p85 antibody, CBFA2T2 antibody, myeloid translocation gene-related protein 1 antibody, MTG8-like protein antibody, MTG8-related protein 1 antibody, ETO homolog on chromosome 20 antibod" in publications.

  5. What is the shipping cost for "CBFA2T2 Antibody (OAGA00723)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CBFA2T2 Antibody (OAGA00723)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CBFA2T2 Antibody (OAGA00723)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "67 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CBFA2T2 Antibody (OAGA00723)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "CBFA2T2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CBFA2T2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CBFA2T2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CBFA2T2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CBFA2T2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CBFA2T2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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