CAZIP Antibody (OAPB01058)

Catalog No: OAPB01058

Size:100UG

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Western blot analysis of CAZIP in A20 cell lysate with CAZIP antibody at (A) 0.5 and (B) 1 μg/mL.

Immunohistochemistry of CAZIP in mouse heart tissue with CAZIP antibody at 5 μg/mL.

Immunofluorescence of CAZIP in mouse heart tissue with CAZIP antibody at 20 μg/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse
• Product Format: Liquid. CAZIP Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: CAZIP antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: CAZIP antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human CAZIP. The immunogen is located within amino acids 1300 - 1350 of CAZIP.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-CAZIP antibody is Catalog # OEPB03175
• Application Info: CAZIP antibody can be used for detection of CAZIP by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Du Puy L, Beqqali A, Monshouwer-Kloots J, et al. CAZIP, a novel protein expressed in the developing heart and nervous system. Dev. Dyn.2009; 238:2903-11.;Jiang K, Wang J, Liu J, et al. TIP150 interacts with and targets MCAK at the microtubule plus ends. EMBO Rep.2009; 10:857-65.;

Target Info

• Gene Symbol: MTUS2
• Gene Full Name: microtubule associated scaffold protein 2
• Alias Symbols: +TIP of 150 kDa;cardiac zipper protein;CAZIP;ICIS;KIAA0774;microtubule associated tumor suppressor candidate 2;microtubule plus-end tracking protein TIP150;microtubule-associated tumor suppressor candidate 2;TIP150;tracking protein of 150 kDa.
• NCBI Gene Id: 23281
• Protein Name: Microtubule-associated tumor suppressor candidate 2|microtubule-associated tumor suppressor candidate 2 isoform a [Homo sapiens]
• Description of Target: Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip.
• Uniprot ID: Q5JR59
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_001028774