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Catalog No: OASE00253-Biotin
Size:100ug
Price: $429.00
SKU
OASE00253-Biotin
Availability: Domestic: within 3-5 days delivery | International: 3-5 days
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CaV3.1 Antibody : Biotin (OASE00253-Biotin)

Datasheets/ManualsPrintable datasheet for OASE00253-Biotin
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityMonoclonal
CloneS178A-9
IsotypeIgG1
HostMouse
ConjugationBiotin
ApplicationWB, IHC
Additional InformationBackground Info: Detects ~<200kDa. Does not cross-react with Cav3.2
::Scientific Background: Calcium channel CaV3.1 (a1G) is a low-voltage-activated T-type calcium channel. Such T-type channels are expressed throughout the body. In the heart, they may be involved in pacemaker current. In neurons, these channels may play a secondary pacemaker role (3). With the ubiquitous expression, it is not surprising that alterations in channel function have been implicated in disease. Drugs that act to block T-type calcium channels are used as anti-hypertensives, antiepileptic's, and blocking of T-type calcium channels may be involved in the action of some anesthetics and antipsychotics as well (3). Much remains to be determined about the precise cellular localization, in vivo physiological roles, roles in disease states and possible routes to modulate their structure/function to ameliorate effects of disease.
::Certificate of Analysis: 1ug/mL was sufficient for detection of Cav3.1 in 20ug of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenFusion protein amino acids 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1
PurificationProtein G Purified
Concentration1 mg/ml
Dilution1:1000 (WB)
Storage BufferPBS pH7.4, 50% glycerol
Reference1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.:Sunderland, MA USA.
2. www.iochannels.org
3. Perez-Reyes E. (2003). Physiol. Rev., 83: 117-161.
Gene SymbolCacna1g
Gene Full Namecalcium channel, voltage-dependent, T type, alpha 1G subunit
Alias Symbolsa1, a1G, Cav3., [a]1G, Cav3.1d, alpha-1G, mKIAA1123
NCBI Gene Id12291
Uniprot IDQ9WUT2
Protein Accession #NP_001106284.1
  1. What is the species homology for "CaV3.1 Antibody : Biotin (OASE00253-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "CaV3.1 Antibody : Biotin (OASE00253-Biotin)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "CaV3.1 Antibody : Biotin (OASE00253-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CaV3.1 Antibody : Biotin (OASE00253-Biotin)"?

    This target may also be called "a1, a1G, Cav3., [a]1G, Cav3.1d, alpha-1G, mKIAA1123" in publications.

  5. What is the shipping cost for "CaV3.1 Antibody : Biotin (OASE00253-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CaV3.1 Antibody : Biotin (OASE00253-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CaV3.1 Antibody : Biotin (OASE00253-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CaV3.1 Antibody : Biotin (OASE00253-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CACNA1G"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CACNA1G"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CACNA1G"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CACNA1G"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CACNA1G"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CACNA1G"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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