CAV1 Recombinant Protein (OPCD01924)

Catalog No: OPCD01924

CAV1 Recombinant Protein (OPCD01924) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Human
• Product Format: Lyophilized PBS (pH 7.4) containing 0.01% SKL and 5% Trehalose
• Host: E.coli
• Conjugation: Unconjugated
• Application: SDS-PAGE, WB, ELISA, IP
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser2-Ser104
  Subcellular Location: Membrane
  Isoelectric Point: 5.7
• Reconstitution and Storage: Reconstitute in 10mM PBS (pH 7.4) to a concentration of 0.1-1.0 mg/ml. Do not vortex. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. Avoid repeated freeze/thaw cycles.
• Concentration: 800 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: Prokaryotic Expressed Recombinant
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: CAV1
• Gene Full Name: caveolin 1
• Alias Symbols: CGL3, PPH3, BSCL3, LCCNS, VIP21, MSTP085
• NCBI Gene Id: 857
• Protein Name: Caveolin-1
• Description of Target: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation .
• Uniprot ID: Q03135
• Protein Accession #: NP_001744.2
• Nucleotide Accession #: NM_001753.4
• Molecular Weight: 13 kDa