Search Antibody, Protein, and ELISA Kit Solutions

CAV1 Antibody (OAEB01599)

100 ug
$349.00
In Stock
Request Bulk Order Quote

Gene Symbol:
CAV1
NCBI Gene Id:
857
Protein Name:
Caveolin-1
Swissprot Id:
Q03135
Protein Accession #:
NP_001744.2
Alias Symbols:
CAV1, caveolin 1, caveolae protein, 22kDa, HGNC:1527, CAV, MSTP085, VIP21, caveolae protein, 22-kD, caveolin 1, caveolin 1 caveolae protein, 22kD, caveolin 1, alpha isoform, caveolin 1, beta isoform, cell growth-inhibiting protein 32, BSCL3,
Replacement Item:
This antibody may replace item sc-111219 from Santa Cruz Biotechnology.
Host:
Goat
Clonality:
Polyclonal
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CAV1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CAV1.
Predicted Species Reactivity:
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Predicted Homology Based on Immunogen Sequence:
Cow: 75%; Dog: 83%; Horse: 83%; Human: 100%; Mouse: 83%; Pig: 75%; Rabbit: 83%; Rat: 83%; Sheep: 75%
Complete computational species homology data:
CAV1 Antibody (OAEB01599)
Peptide Sequence:
C-DELSEKQVYDAH
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Datasheets/Manuals:
Printable datasheet for anti-CAV1 antibody - OAEB01599
Purity:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:32000.
Western Blot: Approx 21kDa and 25kDa observed in Human Heart, Lung and Spleen lysates. These bands correspond to earlier findings in literature with different antibodies (Wiechen et al Am J Pathol. 2001 Mar;158(3):833-9, PMID: 11238032). In transfected HEK293 transiently expressing Caveolin 1 a band of approx. 23kDa is observed. This band is not observed in the non-transfected HEK293. This protein has a calculated MW of 20.5kDa according to NP_001744.2. Recommended concentration: 0.3-1ug/ml.
Target Reference:
* Schmidtko A, Gao W, Konig P, Heine S, Motterlini R, Ruth P, Schlossmann J, Koesling D, Niederberger E, Tegeder I, Friebe A, Geisslinger G.; cGMP produced by NO-sensitive guanylyl cyclase essentially contributes to inflammatory and neuropathic pain by using targets different from cGMP-dependent protein kinase I.; J Neurosci. 2008 Aug 20;28(34):8568-76.; Pubmed 18716216
* Cavallo-Medved D, Mai J, Dosescu J, Sameni M, Sloane BF.; Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells.; J Cell Sci. 2005 Mar 15; [Epub ahead of print]; Pubmed 15769846

Product Reviews

Tell us what you think about this item!

Write A Review
    Please, wait...