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Search results for 'PSEN2'


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    PSEN2 ELISA Kit (Bovine) (OKEH06633)

    Protein Name:Presenilin-2
    Catalog #:OKEH06633
    Type: Kit
    Reacts with: Bovine
    Application:
    Product Size: 96 Wells
    Price (USD): $569.00
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    PSEN2 Antibody - middle region (ARP97209_P050)

    Protein Name:This gene encodes a member of the presenilin family. Presenilins are catalytic components of the multi-subunit gamma-secretase complex, which mediates critical cellular processes through cleavage of type I transmembrane proteins including Notch receptors and the amyloid precursor protein. The encoded protein contains eight transmembrane domains and is localized to the endoplasmic reticulum, where it may play a role in calcium homeostasis. Following assembly of the gamma-secretase complex, the encoded protein is cleaved into N- and C-terminal fragments and the activated complex is released from the endoplasmic reticulum. Inactivation of this gene results in impaired synaptic function in a mouse model for Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene.
    Catalog #:ARP97209_P050
    Type: pAb
    Reacts with: Mouse
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
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    PSEN2 Antibody - C-terminal region (OAAB18098)

    Protein Name:
    Catalog #:OAAB18098
    Type: pAb
    Reacts with: Cow, Mouse, Pig, Rat
    Application: WB
    Product Size: 400 ul
    Price (USD): $320.00
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