CASR Antibody - C-terminal region (ARP80604_P050)

Catalog No: ARP80604_P050

Host: Rabbit
Target Name: CASR
Sample Tissue: Human HepG2 Whole Cell lysates
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CASR
• Purification: Affinity purified
• Peptide Sequence: Synthetic peptide located within the following region: SSLGGSTGSTPSSSISSKSNSEDPFPQPERQKQQQPLALTQQEQQQQPLT
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-CASR (ARP80604_P050) antibody is Catalog # AAP80604

Target Info

• Gene Symbol: CASR
• Gene Full Name: calcium sensing receptor
• Alias Symbols: CAR, FHH, FIH, HHC, EIG8, HHC1, NSHPT, PCAR1, hCasR, GPRC2A, HYPOC1
• NCBI Gene Id: 846
• Protein Name: extracellular calcium-sensing receptor
• Description of Target: The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
• Uniprot ID: P41180
• Protein Accession #: NP_000379.2
• Nucleotide Accession #: NM_000388.3
• Protein Size (# AA): 1078
• Molecular Weight: 118 kDa