Size:100ug
$350.00
Discontinued
SKU
OASE00218
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Conjugation Options

OASE00218-FITC Conjugated

OASE00218-HRP Conjugated

OASE00218-Biotin Conjugated

CASPR Antibody (OASE00218)

Catalog#: OASE00218
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This product is Genway GWB-509YA9
More Information
Predicted Species Reactivity Human, Mouse, Rat
Clonality Monoclonal
Clone S65-35
Isotype IgG1
Host Mouse
Application WB, IHC, IP
:: Certificate of Analysis: 1 ug/mL was sufficient for detection of CASPR in 20ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Reconstitution and Storage Store at -20C. Shipping in Blue Ice or 4C.
Replacement Item This antibody may replace item sc-41916 from Santa Cruz Biotechnology.
Immunogen Fusion protein 1308-1381 (cytoplasmic domain) of rat CASPR, accession number
P97846.
Purification Protein G Purified
Concentration 1mg/mL
Datasheets/Manuals Printable datasheet for OASE00218
Application Info WB:1ug/mL
IHC/ICC: 0.1-1ug/mL

IF: 1-10ug/mL
Application Data Background Info: Detects ~220kDa.
Storage Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide
Target Reference 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.,
2. www.iochannels.org,
3. www.en.wikipedia.org/wiki/Caspr,
4. Horresh I., Bar V., Kissil J.L., and Peles E. (2010) J.Neurosci. 30(7): 2480-2489.
Gene Symbol CNTNAP1
Official Gene Full Name contactin associated protein 1
NCBI Gene Id 8506
Description of Target Scientific Background: Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath.Its role is for myelin sheath attachment along with contactin in a cis-complex (3). Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B (4).
Swissprot Id P78357
Protein Accession # NP_003623.1
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express CNTNAP1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express CNTNAP1.
  1. What is the species homology for "CASPR Antibody (OASE00218)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "CASPR Antibody (OASE00218)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "CASPR Antibody (OASE00218)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CASPR Antibody (OASE00218)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "CASPR Antibody (OASE00218)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CASPR Antibody (OASE00218)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CASPR Antibody (OASE00218)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CASPR Antibody (OASE00218)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "CNTNAP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CNTNAP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CNTNAP1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CNTNAP1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CNTNAP1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CNTNAP1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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