Catalog No: ARP50555_P050
Price: $0.00
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ARP50555_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-CASP8AP2 (ARP50555_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human CASP8AP2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: SLKKNISALIKTARVEINRKDEEISNLHQRLSEFPHFRNNHKTARTFDTV
Concentration0.5 mg/ml
Blocking PeptideFor anti-CASP8AP2 (ARP50555_P050) antibody is Catalog # AAP50555 (Previous Catalog # AAPP13848)
ReferenceJeong,E.G., (2008) Pathology 40 (1), 31-34
Gene SymbolCASP8AP2
Gene Full Namecaspase 8 associated protein 2
Alias SymbolsCED-4, FLASH, RIP25
NCBI Gene Id9994
Protein NameCASP8-associated protein 2
Description of TargetThis protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
Uniprot IDQ9UKL3
Protein Accession #NP_036247
Nucleotide Accession #NM_012115
Protein Size (# AA)1982
Molecular Weight223kDa
Protein Interactionsced-3; BCL2L1; PML; CTBP2; CREM; SUMO1; SUMO2; PIAS1; CASP10; TRIM21; UBC; CALM1; UBE2I; SREBF2; GLUL; SP100; CASP8AP2; FADD; TRAF2; CASP8; FAS;
  1. What is the species homology for "CASP8AP2 Antibody - N-terminal region (ARP50555_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "CASP8AP2 Antibody - N-terminal region (ARP50555_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CASP8AP2 Antibody - N-terminal region (ARP50555_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CASP8AP2 Antibody - N-terminal region (ARP50555_P050)"?

    This target may also be called "CED-4, FLASH, RIP25" in publications.

  5. What is the shipping cost for "CASP8AP2 Antibody - N-terminal region (ARP50555_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CASP8AP2 Antibody - N-terminal region (ARP50555_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CASP8AP2 Antibody - N-terminal region (ARP50555_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "223kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CASP8AP2 Antibody - N-terminal region (ARP50555_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CASP8AP2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CASP8AP2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CASP8AP2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CASP8AP2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CASP8AP2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CASP8AP2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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