CASP2 Antibody (OAPA00221)

Catalog No: OAPA00221 (Formerly GWB-BSP822)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
• Clonality: Monoclonal
• Clone: P1C10AT.
• Isotype: Mouse IgG2b heavy chain and kappa light chain.
• Host: Mouse
• Application: WB
  Product Type: Mouse Anti Human Monoclonal.
  Product Introduction: Caspase-2 is a protein which belongs to the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases has a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of Caspase-2 is induced by a variety of apoptotic stimuli.
• Reconstitution and Storage: For periods up to 1 month store at 4C, for longer periods of time, store at -20C. Prevent freeze thaw cycles.
  Stability: 12 months at -20C. 1 month at 4C.
• Immunogen: The immunogen for anti-CASP2 antibody: anti-human Caspase-2 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Caspase-2 amino acids 32-169 purified from E. coli.
• Purity: Caspase-2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
• Application Info: Caspase-2 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.

Target Info

• Gene Symbol: Casp2
• Alias Symbols: Casp, Ich-, Nedd, ICH-1, Nedd2, CASP-2, NEDD-2
• NCBI Gene Id: 12366
• Protein Name: Caspase-2
• Description of Target: Mouse Anti Human Caspase-2
• Uniprot ID: P29594