Catalog No: ARP87181_P050
Price: $0.00
SKU
ARP87181_P050
Availability: Domestic: within 24 hours delivery | International: 3-5 days
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for anti-CASP12 (ARP87181_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human CASP12
PurificationAffinity purified
Peptide SequenceSynthetic peptide located within the following region: LGMRDLLENLGYSVVIKENLTAQEMETALRQFAAHPEHQSSDSTFLVFMS
Concentration0.5 mg/ml
Blocking PeptideFor anti-CASP12 (ARP87181_P050) antibody is Catalog # AAP87181
Gene SymbolCASP12
Gene Full Namecaspase 12 (gene/pseudogene)
Alias SymbolsCASP-12, CASP12P1
NCBI Gene Id100506742
Protein NameInactive caspase-12
Description of TargetCaspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.
Uniprot IDQ6UXS9-3
Protein Accession #NP_001177945.2
Nucleotide Accession #NM_001191016.2
Protein Size (# AA)257
Molecular Weight28 kDa
  1. What is the species homology for "CASP12 Antibody - middle region (ARP87181_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "CASP12 Antibody - middle region (ARP87181_P050)"?

    This item is available "Domestic: within 24 hours delivery | International: 3-5 days".

  3. What buffer format is "CASP12 Antibody - middle region (ARP87181_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CASP12 Antibody - middle region (ARP87181_P050)"?

    This target may also be called "CASP-12, CASP12P1" in publications.

  5. What is the shipping cost for "CASP12 Antibody - middle region (ARP87181_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CASP12 Antibody - middle region (ARP87181_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CASP12 Antibody - middle region (ARP87181_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "28 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CASP12 Antibody - middle region (ARP87181_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CASP12"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CASP12"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CASP12"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CASP12"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CASP12"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CASP12"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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