Size:100ug
$350.00
Discontinued
SKU
OASE00214
Request Bulk
Order Quote
Aviva's
Satisfaction
Guarantee
Contact Us:
  • Toll Free: (888)880-0001
  • Phone: (858)552-6979
  • Email: info@avivasysbio.com
Shipping Info:
  • $40: Antibody & Protein in US
  • $50: 1-2 Kits in US
  • Contact us for international orders.

Conjugation Options

OASE00214-FITC Conjugated

OASE00214-HRP Conjugated

OASE00214-Biotin Conjugated

CASK Antibody (OASE00214)

Catalog#: OASE00214
Inquire
This product is Genway GWB-S8VPG5
More Information
Predicted Species Reactivity Mouse, Rat, Human, Zebrafish, Xenopus
Clonality Monoclonal
Clone S56A-50
Isotype IgG1
Host Mouse
Application WB, IHC, IP
Additional Information Background Info: Detects ~100kDa.
:: Scientific Background: CASK (calmodulin sensitive kinase) is a ~112kDa member of the membrane associated quanylate kinase (MAGUK)
protein family. It is an adaptor protein with a
calcium/calmodulin-dependent protein kinase domain, a
SH3 domain, aguanylate kinase homology domain (GUK)
and a PDZ domain. CASK links transmembrane proteins
to the cytoskeleton and signaling molecules. In
particular, CASK binds to Neurexin to stabilize pre- and
post-synaptic structrures (1). While most of CASK proteins
are cytoplasmic, a portion of the protein enters the
nucleus, where it acts as a transcriptional co-activator (2).
Manifesting the importance of CASK, transgenic mice with
insertional mutations die within 24 hours of births (3).
CASK is also localized in the nuclei of basal keratinocytes
in newborn rodent skin and developing hair follicles. It
may play a role in wound healing (4).
:: Certificate of Analysis: 1 ug/mL was sufficient for detection of CASK in 20 ug of rat brain tissue extract by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Reconstitution and Storage Store at -20C. Shipping in Blue Ice or 4C.
Replacement Item This antibody may replace item sc-10777 from Santa Cruz Biotechnology.
Immunogen Fusion protein amino acids 318-415 of rat CASK/Lin2
Purification Protein G Purified
Concentration 1mg/mL
Datasheets/Manuals Printable datasheet for OASE00214
Dilution 1:1000 (WB)
Storage Buffer PBS pH7.4, 50% glycerol
Target Reference 1. Hata Y., et al. (1996). J Neurosci. 16: 2488-2494.
2. Hsueh Y.P., et al. (2000) Nature. 404: 298-302.
3. Laverty H.G., and Wilson J.B. (1998) Genomics. 53: 29-41.
4. Ojeh N., Pekovic V., Jahoda C., and Maatta A. (2008) J
Cell Sci. 121(16): 2705-2717.
Gene Symbol Cask
Official Gene Full Name calcium/calmodulin-dependent serine protein kinase (MAGUK family)
NCBI Gene Id 29647
Swissprot Id Q62915
Protein Accession # NP_071520.1
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express Cask.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express Cask.
  1. What is the species homology for "CASK Antibody (OASE00214)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse, Rat, Human, Zebrafish, Xenopus".

  2. How long will it take to receive "CASK Antibody (OASE00214)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "CASK Antibody (OASE00214)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CASK Antibody (OASE00214)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "CASK Antibody (OASE00214)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CASK Antibody (OASE00214)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CASK Antibody (OASE00214)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CASK Antibody (OASE00214)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "CASK"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CASK"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CASK"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CASK"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CASK"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CASK"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:CASK Antibody (OASE00214)
Your Rating
We found other products you might like!