CAPN6 Antibody - middle region (OAAB08821)

Catalog No: OAAB08821

Size:400ul

CAPN6 Antibody (Center) (Cat. #OAAB08821) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CAPN6 antibody detected the CAPN6 protein (arrow).

CAPN6 is strongly supported by BioGPS gene expression data to be expressed in HL60

CAPN6 Antibody (Center) (Cat. #OAAB08821)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CAPN6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC
• Additional Information: Precautions: CAPN6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity)
  Cellular Location: Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, spindle. Note=During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle
  Tissue Location: Expressed only in placenta.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This CAPN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-419 amino acids from the Central region of human CAPN6.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  CAPN6 is strongly supported by BioGPS gene expression data to be expressed in HL60

• Application Info: WB: 1:1000
  IHC-P: 1:10~50

Target Info

• Gene Symbol: CAPN6
• Alias Symbols: CANPX, CAPNX, CalpM, DJ914P14.1
• NCBI Gene Id: 827
• Protein Name: Calpain-6
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q9Y6Q1
• Protein Accession #: NP_055104.2
• Molecular Weight: 74576 Da