CAPN2 Recombinant Protein (OPCD01860)

Catalog No: OPCD01860

CAPN2 Recombinant Protein (OPCD01860) using SDS-PAGE

CAPN2 Recombinant Protein (OPCD01860) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Leu45-Asp514
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: >95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: CAPN2
• Gene Full Name: calpain 2
• Alias Symbols: calcium-activated neutral proteinase 2;calpain 2, (m/II) large subunit;calpain 2, large [catalytic] subunit;calpain 2, large subunit;Calpain large polypeptide L2;calpain M-type;calpain, large polypeptide L2;calpain-2 catalytic subunit;Calpain-2 large subunit;CANP 2;CANP2;CANPL2;CANPml;M-calpain;mCANP;millimolar-calpain.
• NCBI Gene Id: 824
• Protein Name: Calpain-2 catalytic subunit
• Description of Target: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).
• Uniprot ID: P17655
• Protein Accession #: NP_001139540.1
• Nucleotide Accession #: NM_001146068.1
• Protein Size (# AA): Leu45~Asp514
• Molecular Weight: 57kDa