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CAPN2 Antibody (OALA08938)

50 uL
$539.00
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Gene Symbol:
CAPN2
NCBI Gene Id:
824
Official Gene Full Name:
calpain 2
Protein Name:
calpain-2 catalytic subunit
Swissprot Id:
P17655
Protein Accession #:
NP_001139540.1
Nucleotide Accession #:
NM_001146068.1
Alias Symbols:
CAPN2, Calpain 2, large subunit, Calpain ii, Calpain, large polypeptide L2, Calpain-2 catalytic subunit, Calpain 2, Calpain large polypeptide L2, Calpain-2 large subunit, CANP 2, Calpain M-type, CANP2, CANPL2, CANPml, M-type calpain, M-calpain, MCANP ...
Replacement Item:
This antibody may replace item sc-271856 from Santa Cruz Biotechnology.
Description of Target:
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Mouse
Clonality:
Monoclonal
Purification:
Immunoaffinity purified
Application:
FC, IHC-P, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CAPN2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CAPN2.
Immunogen:
M-Calpain antibody was raised against full length human recombinant protein of human CAPN2(NP_001739) produced in HEK293T cell.
Product Format:
Liquid. PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Reconstitution and Storage:
Store at -20C in small aliquots. Minimize freeze-thaw cycles.
Datasheets/Manuals:
Printable datasheet for anti-CAPN2 (OALA08938) antibody
Specificity:
Human CAPN2 / Calpain 2 / M-Calpain
Clone:
1F4
Isotype:
IgG2a
Application Info:
IHC - Paraffin (10 ug/ml)
Western blot (1:500 - 1:2000)
Flow Cytometry (1:100)
Publications:

Butler, CT; Reynolds, AL; Tosetto, M; Dillon, ET; Guiry, PJ; Cagney, G; O'Sullivan, J; Kennedy, BN; A Quininib Analogue and Cysteinyl Leukotriene Receptor Antagonist Inhibits Vascular Endothelial Growth Factor (VEGF)-independent Angiogenesis and Exerts an Additive Antiangiogenic Response with Bevacizumab. 292, 3552-3567 (2017). FC, IHC-P, WB, Mouse, Rat, Human, Monkey 28035003

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