CANT1 Antibody - N-terminal region (OAAB05418)

Catalog No: OAAB05418

Size:400UL

Western blot analysis of CANT1 Antibody (N-term) in Jurkat, A375, Y79, WiDr cell lysates (35ug/lane). CANT1 (arrow) was detected using the purified Pab.

CANT1 Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: FC,WB
• Additional Information: Function: Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis.
  Cellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Processed form: Secreted
  Tissue Location: Widely expressed
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This CANT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CANT1.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  FC: 1:10~50
• Other Applications Image 1 Data: CANT1 Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Target Info

• Gene Symbol: CANT1
• Alias Symbols: apyrase 1 homolog (C. lectularius), apyrase homolog, Ca2+-dependent endoplasmic reticulum nucleoside diphosphatase, DBQD, DBQD1, EDM7, micromelic dwarfism with vertebral and metaphyseal abnormalities and advanced carpotarsal ossification, putative MAPK-activating protein PM09, putative NF-kappa-B-activating protein 107, SCAN-1, SCAN1, SHAPY, soluble Ca-activated nucleotidase, isozyme 1, soluble calcium-activated nucleotidase 1, soluble calcium-activated nucleotidase SCAN-1.
• NCBI Gene Id: 124583
• Protein Name: Soluble calcium-activated nucleotidase 1|soluble calcium-activated nucleotidase 1 [Homo sapiens]
• Description of Target: Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP (PubMed:12234496, PubMed:15248776, PubMed:15006348, PubMed:16835225). Involved in proteoglycan synthesis (PubMed:22539336).
• Uniprot ID: Q8WVQ1
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_001153244.1,NP_001153245.1,NP_620148.1
• Molecular Weight: 44840