CAMP Antibody (OAAI00351)

Catalog No: OAAI00351

Size:100UG

ELISA Plot: Adenosine-3', 5'-cyclic AMP immorbolized onto plates, followed by addition of stand cyclic AMP. The mouse anti c-AMP was added subsequentially, and visiualized by chromatogenic substrate. Each sample was triplicate. IC50 was then calculated.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Clonality: Monoclonal
• Clone: ABM486
• Isotype: Mouse IgG1
• Host: Mouse
• Application: Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
• Additional Information: Background: Cyclic adenosine monophosphate (cAMP) is an intracellular mediator that plays an important role in a variety of hormone signaling. It’s been known as an universal cytoplasmic second messenger in drug discovery due to the involvement of G-Protein Coupled Receptors (GPCR) signaling events where the receptors are activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, etc.
  Positive Control: C-AMP-BSA
  Cellular Location: Cytoplasmic
• Reconstitution and Storage: The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
• Immunogen: A chemically linked 3', 5'-Cyclic Adenosine Monophosphate (cAMP)
• Purification: The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
• Concentration: 100ug/200ul
• Formulation: This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Application Info: WB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: Not tested
• Reference: Chika Funaki, et al, Role of cAMP inhibition of p44/p42 mitogen-activated protein kinase in potentiation of protein secretion in Rat lacrimal gland. Am J Physiol Cell Physiol 293: C1551-C1560, 2007.
  

Target Info

• Gene Symbol: CAMP
• Gene Full Name: Cathelicidin antimicrobial peptide
• Protein Name: Cathelicidin antimicrobial peptide
• Description of Target: Cyclic adenosine monophosphate (cAMP) is an intracellular mediator that plays an important role in a variety of hormone signaling. It's been known as an universal cytoplasmic second messenger in drμg discovery due to the involvement of G-Protein Coupled Receptors (GPCR) signaling events where the receptors are activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, etc.
• Uniprot ID: P49913
• Protein Accession #: NP_004336.3
• Nucleotide Accession #: NM_004345.4