CAMKK2 Antibody (OAGA00666)

Catalog No: OAGA00666

Size:100 ul

Sample (30 ug of whole cell lysate)
A: U87-MG
10% SDS PAGE
OAGA00666 diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded U87 xenograft, using CaMKK beta(OAGA00666) antibody at 1:500 dilution.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC-FFPE, WB
• Additional Information: Background: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq]
  Positive Controls: PC-3
  Cellular Localization: Cytoplasm
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 498 of CaMKK beta
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 0.73 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: CAMKK2
• Gene Full Name: Calcium/calmodulin-dependent protein kinase kinase 2
• Alias Symbols: CAMKK, CAMKKB
• NCBI Gene Id: 10645
• Protein Name: Calcium/calmodulin-dependent protein kinase kinase 2
• Uniprot ID: Q96RR4
• Protein Accession #: NP_001257414.1
• Molecular Weight: 55 kDa