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Catalog No: OPCD02435
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OPCD02435
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Datasheets/ManualsPrintable datasheet for CALR Recombinant Protein (OPCD02435)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Asp199-Tyr308
::Subcellular Location: Plasma, Endoplasmic reticulum lumen
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His Tag
Gene SymbolCalr
Gene Full Namecalreticulin
Alias SymbolsCalregulin;calreticulin;CR;CRP55;CRT;endoplasmic reticulum resident protein 60;ERp60;HACBP.
NCBI Gene Id12317
Protein NameCalreticulin
Description of TargetCalcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).
Uniprot IDP14211
Protein Accession #NP_031617.1
Nucleotide Accession #NM_007591.3
Protein Size (# AA)Asp199~Tyr308
Molecular Weight22kDa
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