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CAD cDNA (ANA10730)

1ug
$189.00
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Reconstitution and Storage:
Centrifuge the vials after receiving and add 5 μl ddH2O
Gene Symbol:
CAD
NCBI Gene Id:
790
Alias Symbols:
CAD
Protein Name:
CAD protein
Description of Target:
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
Swissprot Id:
P27708
Protein Accession #:
NP_004332
Nucleotide Accession #:
BC065510
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CAD.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CAD.
Tag:
None
Protein Interactions:
UBC; TUBG1; TP53; SUMO2; SPRTN; STAU1; LGR4; SUMO1; NEDD8; WWOX; NEDD4; FBXO6; HDAC6; ILK; CDK2; HDAC11; HTRA2; TP63; NOS2; ITGA4; RUVBL1; XPO1; VARS; TUBB2A; TUBA4A; SMARCC2; SMARCA4; RPS3; PSMD1; PSMC2; RUVBL2; TUBB4B; SHC1; SMAD2; GRB2; CBL; CUL3; FBXO
Datasheets/Manuals:
Printable datasheet for anti-CAD (ANA10730) antibody

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