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CACNA2D1 Antibody (OAEB01261)

100 ug
$349.00
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Gene Symbol:
CACNA2D1
NCBI Gene Id:
781
Protein Name:
Putative uncharacterized protein CACNA2D1 EMBL AAC78619.1
Swissprot Id:
O95026
Protein Accession #:
NP_000713.2
Alias Symbols:
CACNA2D1, calcium channel, voltage-dependent, alpha 2/delta subunit 1, CACNA2, CACNL2A, CCHL2A, MHS3, H_DJ0560O14.1, WUGSC:H_DJ0560O14.1, calcium channel, L type, alpha 2 polypeptide, dihydropyridine-sensitive L-type, calcium channel alpha-2/delt
Replacement Item:
This antibody may replace item sc-104118 from Santa Cruz Biotechnology.
Host:
Goat
Clonality:
Polyclonal
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CACNA2D1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CACNA2D1.
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rat: 92%
Complete computational species homology data:
CACNA2D1 Antibody (OAEB01261)
Peptide Sequence:
C-QEIFNKYNKDKKVR
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Datasheets/Manuals:
Printable datasheet for anti-CACNA2D1 antibody - OAEB01261
Purity:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:16000.
Western Blot: Approx 140kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 123kDa according to NP_000713.2). Recommended concentration: 0.03-0.1ug/ml.
Target Reference:
* Hullin R, Matthes J, von Vietinghoff S, Bodi I, Rubio M, D'Souza K, Friedrich Khan I, Rottlander D, Hoppe UC, Mohacsi P, Schmitteckert E, Gilsbach R, Bunemann M, Hein L, Schwartz A, Herzig S.; Increased Expression of the Auxiliary beta(2)-subunit of Ventricular L-type Ca Channels Leads to Single-Channel Activity Characteristic of Heart Failure.; PLoS ONE. 2007 Mar 14;2:e292.; Pubmed 17356701
Publications:

Bannister, J. P. et al. Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells. J. Biol. Chem. 286, 15058-66 (2011). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat 21357696

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