CACNA2D1 Antibody (OAEB01261)

Catalog No: OAEB01261 (Formerly GWB-66F167)

Size:100UG

OAEB01261 (0.03ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Clonality: Polyclonal
• Host: Goat
• Application: WB
• Reconstitution and Storage: Aliquot and store at -20C. Minimize freezing and thawing.
• Immunogen: CACNA2D1
• Purification: Ammonium Sulfate Precipitated; Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rat: 92%
• Peptide Sequence: C-QEIFNKYNKDKKVR
• Concentration: 0.5 mg/ml
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Application Info: Peptide ELISA: antibody detection limit dilution 1:16000.
  Western Blot: Approx 140kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 123kDa according to NP_000713.2). Recommended concentration: 0.03-0.1ug/ml.
• Reference: * Hullin R, Matthes J, von Vietinghoff S, Bodi I, Rubio M, D'Souza K, Friedrich Khan I, Rottlander D, Hoppe UC, Mohacsi P, Schmitteckert E, Gilsbach R, Bunemann M, Hein L, Schwartz A, Herzig S.; Increased Expression of the Auxiliary beta(2)-subunit of Ventricular L-type Ca Channels Leads to Single-Channel Activity Characteristic of Heart Failure.; PLoS ONE. 2007 Mar 14;2:e292.; Pubmed 17356701
• Publications:

  Bannister, J. P. et al. Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells. J. Biol. Chem. 286, 15058-66 (2011). 21357696

  Expression of microRNAs is essential for arterial myogenic tone and pressure-induced activation of the PI3-kinase/Akt pathway. Cardiovasc Res. 101, 288-96 (2014) 24233972

• Description:
  View product citations for CACNA2D1 Antibody (OAEB01261) on CiteAb

Target Info

• Gene Symbol: Cacna2d1|CACNA2D1
• Gene Full Name: calcium channel, voltage-dependent, alpha2/delta subunit 1|calcium voltage-gated channel auxiliary subunit alpha2delta 1
• Alias Symbols: Ca(v)alpha2delta1;Cac;Cacna2;CACNL2A;Calcium channel subunit alpha 2 delta (dihydropyridine - sensitive L-type);calcium channel, L type, alpha 2 polypeptide;calcium channel, voltage-dependent, alpha 2/delta subunit 1;calcium channel, voltage-dependent, alpha2/delta subunit 1;Cchl;Cchl2a;CCHLA2;DHSCCA;dihydropyridine-sensitive calcium channel alpha 2;dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit;LINC01112;lncRNA-N3;voltage-dependent calcium channel alpha2/delta-1;voltage-dependent calcium channel subunit alpha-2/delta-1;voltage-gated calcium channel subunit alpha-2/delta-1.
• NCBI Gene Id: 12293|25399|781
• Protein Name: Putative uncharacterized protein CACNA2D1 EMBL AAC78619.1
• Uniprot ID: O95026
• Protein Accession #: NP_000713.2
• Molecular Weight: 123