Catalog No: OPCD01817
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OPCD01817
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Datasheets/ManualsPrintable datasheet for CACNA1H Recombinant Protein (OPCD01817)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ser2160-Val2359
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity>95%
SourceE.coli
TagN-terminal His and GST Tag
Gene SymbolCACNA1H
Alias SymbolsVoltage-gated calcium channel subunit alpha Cav3.2.
Protein NameVoltage-dependent T-type calcium channel subunit alpha-1H
Description of TargetVoltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group. A particularity of this type of channel is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons. In the adrenal zona glomerulosa, participates in the signaling pathway leading to aldosterone production in response to either AGT/angiotensin II, or hyperkalemia.
Uniprot IDO88427
Protein Size (# AA)Ser2160~Val2359
Molecular Weight51kDa
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