CA11 Antibody (OAGA01075)

Catalog No: OAGA01075

Size:100 ul

Sample (30 ug of whole cell lysate)
A: A431
10% SDS PAGE
OAGA01075 diluted at 1:500

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Additional Information: Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq]
  Positive Controls: A431
  Cellular Localization: Secreted
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 311 of CA11 (Uniprot ID#O75493)
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 0.81 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: CA11
• Gene Full Name: Carbonic anhydrase-related protein 11
• Alias Symbols: CA-RP, CA-XI, CARP-2, CARPX1, CA-RP II
• NCBI Gene Id: 770
• Protein Name: Carbonic anhydrase-related protein 11
• Uniprot ID: O75493
• Protein Accession #: NP_001208.2
• Molecular Weight: 36 kDa