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Catalog No: OPCD01771
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OPCD01771
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Datasheets/ManualsPrintable datasheet for C4BPA Recombinant Protein (OPCD01771)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Leu358-His469
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolC4bp
Gene Full Namecomplement component 4 binding protein
Alias SymbolsAI195242;C4b-binding protein;C4bpa.
NCBI Gene Id12269
Protein NameC4b-binding protein
Description of TargetControls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with serum amyloid P component.
Uniprot IDP08607
Protein Accession #NP_031602.3
Nucleotide Accession #NM_007576.3
Protein Size (# AA)Leu358~His469
Molecular Weight20kDa
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