C4BPA Recombinant Protein (OPCD01770)

Catalog No: OPCD01770

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gln548-Leu597
  Subcellular Location: Secreted
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: C4BPA
• Gene Full Name: complement component 4 binding protein alpha
• Alias Symbols: C4b-binding protein alpha chain;C4BP;proline-rich protein;PRP.
• NCBI Gene Id: 722
• Protein Name: C4b-binding protein alpha chain
• Description of Target: Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
• Uniprot ID: P04003
• Protein Accession #: NP_000706.1
• Nucleotide Accession #: NM_000715.3
• Protein Size (# AA): Gln548~Leu597
• Molecular Weight: 7kDa