Catalog No: OPCA01492
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OPCA01492
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Datasheets/ManualsPrintable datasheet for C1QA Recombinant Protein (Mouse) (OPCA01492) (OPCA01492)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatLyophilized 10mM Tris-HCl, 1mM EDTA, 6% Trehalose (pH 8.0)
HostMouse
Reconstitution and StorageWe recommend that this briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/ml. We recommend to add 5-50% glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Store working aliquots at 4°C for up to one week. Repeated freeze/thaw cycles are not recommended.
PurificationAffinity purified using IMAC
PurityGreater than 90% as determined by SDS-PAGE.
Peptide SequenceFull of Length of Mature Protein: EDVCRAPNGKDGAPGNPGRPGRPGLKGERGEPGAAGIRTGIRGFKGDPGESGPPGKPGNVGLPGPSGPLGDSGPQGLKGVKGNPGNIRDQPRPAFSAIRQNPMTLGNVVIFDKVLTNQESPYQNHTGRFICAVPGFYYFNFQVISKWDLCLFIKSSSGGQPRDSLSFSNTNNKGLFQVLAGGTVLQLRRGDEVWIEKDPAKGRIYQGTEADSIFSGFLIFPSA
SourceE.coli
Protein Range23-245 aa
TagN-terminal 6xHis-SUMO-tagged
ReferenceLineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009)
Gene SymbolC1qa
Gene Full Namecomplement component 1, q subcomponent, alpha polypeptide
Alias SymbolsAdic;adiponectin c;AI255395;C1q;complement C1q subcomponent subunit A.
NCBI Gene Id12259
Protein NameComplement C1q subcomponent subunit A
Description of TargetC1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Uniprot IDP98086
Protein Accession #NP_031598.2
Nucleotide Accession #NM_007572.2
Protein Size (# AA)Recombinant
Molecular Weight40 kDa
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