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C-raf Antibody (OAPB01117)

0.1 mg
$375.00
In Stock
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Conjugation Options

OAPB01117-FITC Conjugated

OAPB01117-HRP Conjugated

OAPB01117-Biotin Conjugated

Gene Symbol:
RAF1
NCBI Gene Id:
5894
Protein Name:
RAF proto-oncogene serine/threonine-protein kinase
Swissprot Id:
P04049
Alias Symbols:
NS5, CRAF, Raf-1, c-Raf,
Replacement Item:
This antibody may replace item sc-113164 from Santa Cruz Biotechnology.
Description of Target:
v-raf murine sarcoma viral oncogene homolog 1
Host:
chicken
Clonality:
Polyclonal
Purification:
Affinity chromatography purified via peptide column
Application:
ELISA, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express RAF1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RAF1.
Immunogen:
The immunogen for anti-C-raf antibody: antibody was raised against an 19 amino acid peptide near the amino terminus of human C-raf.
Predicted Species Reactivity:
Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Human; Mouse; Rat
Reconstitution and Storage:
C-raf antibody can be stored at 4C, stable for three months. Store at -20C for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Blocking Peptide:
For anti-C-raf antibody is Catalog # OEPB03233
Datasheets/Manuals:
Printable datasheet for anti-C-raf antibody - OAPB01117
Application Info:
C-raf antibody can be used for detection of C-raf by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
:::
Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Target Reference:
Howe LR, Leevers SJ, Gomez N, et al. Activation of the MAP kinase pathway by the protein kinase raf. Cell1992; 71:335-42.;Chang F, Steelman LS, Shelton JG, et al. Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway. Int. J. Oncol.2003; 22:469-80.;Pandit B, Sarkozy A, Pennacchio LA, et al. Gain-of-function RAF1 mutations cause Noonan and LEOPARD syndromes with hypertrophic cardiomyopathy. Nat. Genet.2007; 39:1007-12.;

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