BZLF1 Recombinant Protein (HHV-4) (OPCA02106)

Catalog No: OPCA02106

BZLF1 Recombinant Protein (Epstein-Barr virus ) (OPCA02106) in SDS-PAGE showing the molecular weight of approximately 42.8 kDa.

Product Info

• Predicted Species Reactivity: Epstein-Barr virus|Epstein-Barr Virus|Human Gammaherpesvirus 4
• Product Format: Lyophilized 10mM Tris-HCl, 1mM EDTA, 6% Trehalose (pH 8.0)
• Host: Epstein-Barr virus
• Reconstitution and Storage: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/ml. We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Purification: Affinity purified using IMAC
• Purity: Greater than 90% as determined by SDS-PAGE.
• Peptide Sequence: Full Length: MMDPNSTSEDVKFTPDPYQVPFVQAFDQATRVYQDLGGPSQAPLPCVLWPVLPEPLPQGQLTAYHVSTAPTGSWFSAPQPAPENAYQAYAAPQLFPVSDITQNQQTNQAGGEAPQPGDNSTVQTAAAVVFACPGANQGQQLADIGVPQPAPVAAPARRTRKPQQPESLEECDSELEIKRYKNRVASRKCRAKFKQLLQHYREVAAAKSSENDRLRLLLKQMCPSLDVDSIIPRTPDVLHEDLLNF
• Source: E.coli
• Protein Range: 1-245aa
• Tag: N-terminal 6xHis-SUMO-tagged

Target Info

• Reference: TORC2, a coactivator of cAMP-response element-binding protein, promotes Epstein-Barr virus reactivation from latency through interaction with viral BZLF1 protein.Murata T., Sato Y., Nakayama S., Kudoh A., Iwahori S., Isomura H., Tajima M., Hishiki T., Ohshima T., Hijikata M., Shimotohno K., Tsurumi T.J. Biol. Chem. 284:8033-8041(2009)
• Gene Symbol: BZLF1
• Gene Full Name: protein Zta
• Alias Symbols: HHV4_BZLF1;protein Zta;Zebra.
• NCBI Gene Id: 3783744
• Protein Name: Trans-activator protein BZLF1
• Description of Target: Plays a key role in the switch from latent infection to lytic cycle producing new virions. Acts as a transcription factor, inducing early lytic cycle genes, and as a origin binding protein for genome replication. BZLF1 activates the promoter of another EBV gene (BSLF2+BMLF1).
• Uniprot ID: P03206
• Protein Accession #: YP_401673.1
  
• Nucleotide Accession #: NC_007605.1
• Protein Size (# AA): Recombinant
• Molecular Weight: 43 kDa