BSK Recombinant Protein (Fruit fly) (OPCA04242)

Catalog No: OPCA04242

Product Info

• Predicted Species Reactivity: Drosophila melanogaster
• Product Format: Liquid or Lyophilized powder
• Additional Information: Species Specificity Detail: Drosophila melanogaster (Fruit fly)
• Reconstitution and Storage: -20°C or -80°C
• Formulation: Tris-base, 50% glycerol
• Purity: Greater than 90% as determined by SDS-PAGE.
• Peptide Sequence: MTTAQHQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVDEREHTVEQWKELIYEEVMDYEAHNTNNRTR
• Protein Sequence: MTTAQHQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVDEREHTVEQWKELIYEEVMDYEAHNTNNRTR
• Storage Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Source: E.coli
• Protein Range: 1-372 aa
• Tag: N-terminal 6xHis-tagged

Target Info

• Reference: A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila.Sluss H.K., Han Z., Barrett T., Davis R.J., Ip Y.T.Genes Dev. 10:2745-2758(1996).
• Gene Symbol: bsk
• Gene Full Name: basket
• Alias Symbols: basket;BSK;bsk-PB;bsk-PE;bsk-PF;CG5680;CG5680-PB;CG5680-PE;CG5680-PF;c-Jun aminoterminal kinase;c-Jun N-terminal kinase;c-Jun-N-terminal kinase;DBSK/JNK;DJNK;D-JNK;DJNK/bsk;D-junk;Dmel\CG5680;Dmel_CG5680;DmJNK;dNJNK;JNK;jnk (bsk);JNK/SAPK;JUN kinase;Jun NH2-terminal kinase;Jun N-terminal kinase;Junk;Jun-kinase;Jun-N terminal kinase;Jun-N-terminal kinase;pJNK;P-JNK;Protein basket;SAPKa.
• NCBI Gene Id: 44801
• Protein Name: Stress-activated protein kinase JNK
• Description of Target: Responds to activation by environmental stress by phosphorylating a number of transcription factors, primarily components of AP-1 such as Jra and also the transcriptional repressor aop, and thus regulates transcriptional activity (PubMed:9224720). Component of the immune response activated by bacterial infection, and is involved in wound healing and in dorsal closure, a morphogenetic movement during embryogenesis (PubMed:8946915, PubMed:9224720, PubMed:10433922, PubMed:11784101). Functions in the systematic response to wounding acting downstream of the Hayan-phenoloxidase PPO1 cascade (PubMed:22227521). Exhibits cytoprotective activity in neuronal cells in response to wounding to the integument (PubMed:22227521). Controls the expression of a phosphatase, puckered, at the edges of wounded epidermal tissue and in the dorsal epithelium during dorsal closure (PubMed:10433922, PubMed:11784101).
• Uniprot ID: P92208
• Protein Accession #: NP_001162930
• Nucleotide Accession #: NM_001169459
• Protein Size (# AA): Recombinant
• Molecular Weight: 47 kDa